diff --git a/server/routes/genetics.js b/server/routes/genetics.js
new file mode 100644
index 0000000..4437b62
--- /dev/null
+++ b/server/routes/genetics.js
@@ -0,0 +1,158 @@
+const express = require('express');
+const router = express.Router();
+const { getDatabase } = require('../db/init');
+
+// Golden Retriever panel markers tracked by Breedr
+const GR_MARKERS = [
+  'PRA1', 'PRA2', 'prcd-PRA', 'GR-PRA1', 'GR-PRA2',
+  'ICH1', 'ICH2', 'NCL', 'DM', 'MD'
+];
+
+// GET all genetic tests for a dog
+router.get('/dog/:dogId', (req, res) => {
+  try {
+    const db = getDatabase();
+    const tests = db.prepare(`
+      SELECT * FROM genetic_tests
+      WHERE dog_id = ?
+      ORDER BY marker ASC
+    `).all(req.params.dogId);
+
+    // Return a full panel including not_tested placeholders
+    const byMarker = {};
+    for (const t of tests) byMarker[t.marker] = t;
+
+    const panel = GR_MARKERS.map(marker => ({
+      marker,
+      ...(byMarker[marker] || { result: 'not_tested', dog_id: Number(req.params.dogId) })
+    }));
+
+    res.json({ tests, panel });
+  } catch (error) {
+    res.status(500).json({ error: error.message });
+  }
+});
+
+// GET pairing risk — compare sire + dam carrier status
+// Usage: GET /api/genetics/pairing-risk?sireId=1&damId=2
+router.get('/pairing-risk', (req, res) => {
+  try {
+    const { sireId, damId } = req.query;
+    if (!sireId || !damId) {
+      return res.status(400).json({ error: 'sireId and damId are required' });
+    }
+
+    const db = getDatabase();
+
+    const getResults = (dogId) => {
+      const rows = db.prepare('SELECT marker, result FROM genetic_tests WHERE dog_id = ?').all(dogId);
+      const map = {};
+      for (const r of rows) map[r.marker] = r.result;
+      return map;
+    };
+
+    const sireResults = getResults(sireId);
+    const damResults  = getResults(damId);
+
+    const risks = [];
+    for (const marker of GR_MARKERS) {
+      const s = sireResults[marker] || 'not_tested';
+      const d = damResults[marker]  || 'not_tested';
+
+      // Both affected or carrier x carrier = risk
+      if (
+        (s === 'affected' || d === 'affected') ||
+        (s === 'carrier'  && d === 'carrier')
+      ) {
+        risks.push({
+          marker,
+          sire_result: s,
+          dam_result: d,
+          risk_level: (s === 'affected' || d === 'affected') ? 'high' : 'moderate',
+          note: s === 'affected' || d === 'affected'
+            ? 'One or both parents are affected — do not breed'
+            : 'Both parents are carriers — 25% chance of affected offspring',
+        });
+      }
+    }
+
+    res.json({
+      sire_id: Number(sireId),
+      dam_id: Number(damId),
+      risks,
+      safe_to_pair: risks.length === 0,
+    });
+  } catch (error) {
+    res.status(500).json({ error: error.message });
+  }
+});
+
+// GET single genetic test
+router.get('/:id', (req, res) => {
+  try {
+    const db = getDatabase();
+    const test = db.prepare('SELECT * FROM genetic_tests WHERE id = ?').get(req.params.id);
+    if (!test) return res.status(404).json({ error: 'Genetic test not found' });
+    res.json(test);
+  } catch (error) {
+    res.status(500).json({ error: error.message });
+  }
+});
+
+// POST create genetic test
+router.post('/', (req, res) => {
+  try {
+    const { dog_id, test_provider, marker, result, test_date, document_url, notes } = req.body;
+
+    if (!dog_id || !marker || !result) {
+      return res.status(400).json({ error: 'dog_id, marker, and result are required' });
+    }
+    if (!['clear', 'carrier', 'affected', 'not_tested'].includes(result)) {
+      return res.status(400).json({ error: 'result must be: clear | carrier | affected | not_tested' });
+    }
+
+    const db = getDatabase();
+    const dbResult = db.prepare(`
+      INSERT INTO genetic_tests (dog_id, test_provider, marker, result, test_date, document_url, notes)
+      VALUES (?, ?, ?, ?, ?, ?, ?)
+    `).run(dog_id, test_provider || null, marker, result, test_date || null, document_url || null, notes || null);
+
+    const test = db.prepare('SELECT * FROM genetic_tests WHERE id = ?').get(dbResult.lastInsertRowid);
+    res.status(201).json(test);
+  } catch (error) {
+    res.status(500).json({ error: error.message });
+  }
+});
+
+// PUT update genetic test
+router.put('/:id', (req, res) => {
+  try {
+    const { test_provider, marker, result, test_date, document_url, notes } = req.body;
+
+    const db = getDatabase();
+    db.prepare(`
+      UPDATE genetic_tests
+      SET test_provider = ?, marker = ?, result = ?, test_date = ?,
+          document_url = ?, notes = ?, updated_at = datetime('now')
+      WHERE id = ?
+    `).run(test_provider || null, marker, result, test_date || null, document_url || null, notes || null, req.params.id);
+
+    const test = db.prepare('SELECT * FROM genetic_tests WHERE id = ?').get(req.params.id);
+    res.json(test);
+  } catch (error) {
+    res.status(500).json({ error: error.message });
+  }
+});
+
+// DELETE genetic test
+router.delete('/:id', (req, res) => {
+  try {
+    const db = getDatabase();
+    db.prepare('DELETE FROM genetic_tests WHERE id = ?').run(req.params.id);
+    res.json({ message: 'Genetic test deleted successfully' });
+  } catch (error) {
+    res.status(500).json({ error: error.message });
+  }
+});
+
+module.exports = router;